John Boudreau
Professor Emeritus, USC Marshall School of Business | Senior Research Scientist, Center for Effective Organizations | Author: Work Without Jobs & Reinventing Jobs
3x TED Speaker | Author of Data Inspired | Global Expert on AI Culture, Data Strategy & Human-Machine Collaboration
Most organizations have the technology for AI — few have the culture to make it work. Sebastian Wernicke bridges that gap as a 3x TED speaker with 5M+ views, author of Data Inspired, and a practitioner who has generated hundreds of millions in profit by transforming how organizations use data.
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Dr. Sebastian Wernicke has built a rare career at the crossroads of behavioral science and enterprise analytics, translating what we know about human psychology into practical systems that make data and AI actually work inside organizations. With two decades of applied experience spanning Fortune 500s, government institutions, and global consultancies, he has helped leadership teams move beyond data frustration and into measurable, lasting transformation.
TED speaker Sebastian Wernicke has delivered three talks on the TED main stage, accumulating over five million views, a distinction that places him among a select group of practitioners whose ideas have achieved genuine global reach. His appearances have earned acclaim from some of the most demanding audiences in the world, including invited lectures at the Wharton School and Stanford University. Clients such as SAP, BCG, Accenture, Unilever, Munich RE, Mars, and Red Bull have brought him in to address some of their most complex data and organizational challenges.
His core thesis is deceptively simple and increasingly urgent: most organizations have spent billions building the technological operating system for data and AI, yet they continue to fall short because they have never built the cultural operating system to match. The result is a widening gap between technical capability and organizational impact, a gap that costs companies not just efficiency, but competitive relevance.
Published by Georgetown University Press, Data Inspired offers the definitive framework for leaders navigating this gap. Rather than prescribing technical solutions, the book equips executives with the mindsets, habits, and decision-making structures needed to make human-AI collaboration genuinely productive, positioning data not as a reporting function but as a driver of innovation and strategic judgment. For a full overview of the book and what it means for event organizers, read our Data Inspired launch feature.
His work has been recognized by Adam Grant, the #1 New York Times bestselling author of Think Again and Hidden Potential, who has described Wernicke as “a wizard at using evidence to shape successful change.” That endorsement reflects something essential about his approach: evidence-based, immediately actionable, and calibrated to how real organizations behave under pressure.
As a speaker, Sebastian Wernicke brings a rare combination of academic rigor, practitioner credibility, and genuine stage presence. His keynotes generate the kind of audience response that event organizers remember: specific, applicable insights delivered with clarity and wit. Senior leaders leave with concrete frameworks, not vague inspiration, for how to install a cultural operating system for data, how to scale human judgment in an age of machine learning, and how to turn analytics from a source of organizational friction into a source of competitive edge.
Most organizations have spent billions on data and AI infrastructure — and still can't get their people to use it effectively. In this keynote, Wernicke reveals why technological investment alone leads to diminishing returns and introduces the framework for building a Cultural OS: the set of organizational beliefs, behaviors, and decision-making norms that allow human teams to unlock the true potential of intelligent systems. Audiences leave with a concrete diagnostic for where their culture is blocking progress and a prioritized roadmap for closing the gap.
Being "data-driven" has become a business mantra — but Wernicke argues it's the wrong goal. Purely data-driven organizations optimize the present while losing the creative edge needed to invent the future. This keynote introduces the concept of being "Data Inspired": using analytics to amplify human judgment and spark new ideas rather than simply validate existing ones. Drawing on real-world case studies from global companies, Wernicke gives leaders a new mental model for decision-making in the age of machine learning — one that keeps humans strategically in control.
Why do so many data and AI initiatives fail to deliver? In two decades of implementation work across Fortune 500s and government institutions, Wernicke has identified five critical areas where projects most consistently break down: Metrics, Complex Decisions, Decision Rules, Machine Learning, and AI. This keynote goes beyond diagnosis to deliver a practical, executive-level guide for navigating each failure mode — turning analytics from an organizational burden into a genuine driver of competitive advantage.
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