Henrik von Scheel
Industry 4.0 Originator | Professor of Strategy Management | Strategic Advisor to Fortune 500 Companies & Governments | Renowned Futurist & Keynote Speaker
Founder & CEO, UPSIDE Foods | Pioneer of the Cultivated Meat Industry | Mayo Clinic Cardiologist | Stanford Faculty | Global Thinker of the Decade
Uma Valeti walked away from a career as a Mayo Clinic cardiologist to found UPSIDE Foods and create the cultivated meat industry. He secured the first dual FDA and USDA approval for cultivated chicken in the US, raised over $600M, and was named a Global Thinker of the Decade by Foreign Policy. His keynotes are a masterclass in building what no one believed was possible.
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Dr. Uma Valeti is the founder and CEO of UPSIDE Foods, the company that created the cultivated meat industry as we know it. A Mayo Clinic-trained cardiologist who walked away from a promising clinical career to pursue what most of his peers dismissed as science fiction, Valeti founded the company in 2015 — then called Memphis Meats — with a single conviction: that it was possible to grow real meat directly from animal cells, without raising or slaughtering a single animal. A decade later, that conviction has been validated by history.
Innovation speaker Uma Valeti built UPSIDE Foods into the most consequential company in alternative protein, raising over $600 million from a coalition of investors that includes Richard Branson, Bill Gates, Cargill, Tyson Foods, and SoftBank. The company achieved the first dual FDA and USDA regulatory approval for cultivated chicken in the United States — a milestone that rewrote what was considered scientifically and commercially possible. It was also the first to produce multiple species of meat (chicken, duck, and beef) from cultured cells, and the first to break ground on a dedicated cultivated meat production facility. Foreign Policy magazine named Valeti a “Global Thinker of the Decade” in 2019, and he has appeared at SXSW, the Aspen Ideas Festival, and in the Wall Street Journal.
His path from cardiologist to food technology founder was not accidental. In 2005, while practicing interventional cardiology at the Mayo Clinic, Valeti was studying the use of stem cells to repair damaged heart muscle. The connection came quickly: if stem cells could regenerate cardiac tissue, they could grow skeletal muscle tissue too. That insight became the intellectual foundation of UPSIDE Foods. He continued teaching Cardiovascular Medicine at Stanford University while building the company, and serves on the Advisory Council of the Good Food Institute.
The UPSIDE Foods story is as much about category creation as it is about food technology. When Valeti founded the company, there were no regulatory pathways, no established investors in the space, no university programs, and no consumer vocabulary for what cultivated meat even was. By the time the company received federal approval in 2023, it had helped create an industry with over 150 companies operating across every major meat-producing country, billions in cumulative investment, and academic programs at leading agricultural universities. The company has since expanded into life sciences, developing cell culture media infrastructure that has applications well beyond food. It is also actively challenging state-level bans on cultivated meat through the courts, with cases in Florida and Texas moving forward.
As a speaker, Uma Valeti brings something rare to any stage: the founder’s view of a category that did not exist when he started building it. His talks cover the intersection of scientific conviction and commercial reality, what it takes to move technology from science fiction to regulatory approval, how to raise capital for ideas no one has funded before, and the long-term implications of cultivated protein for food security, public health, and animal welfare. For audiences in food, technology, sustainability, entrepreneurship, and healthcare, few speakers offer a more instructive case study in what it actually takes to change an industry from the inside.
Uma Valeti traces the full arc of UPSIDE Foods, from a Mayo Clinic insight about stem cells in 2005 to the first federally approved cultivated chicken in the US. This is not a product pitch. It is a first-person account of what it takes to commercialize a technology that didn't exist, in a regulatory environment with no precedent, for a market that had to be educated before it could be captured. Valeti covers the science, the capital-raising reality, the regulatory journey, and the competitive dynamics of a category he built from scratch. Essential viewing for anyone working at the frontier of deep tech or food systems.
The global food system faces three converging pressures: a growing population, the environmental cost of conventional livestock farming, and mounting concern about animal welfare and antibiotic resistance. In this keynote, Valeti lays out the case for cultivated protein not as a niche alternative but as a structural solution. He covers what has been proven scientifically and commercially, what remains to be solved at scale, and where the industry is headed over the next decade. Suited for sustainability conferences, food and agriculture forums, and events focused on the long-term future of consumption and supply chains.
In 2015, Uma Valeti was a respected Mayo Clinic cardiologist with a tenured path ahead of him. He walked away to found a company in a category that did not exist. This keynote is a candid account of that decision: the intellectual foundation that made it feel less irrational than it looked, the process of building conviction in the face of expert skepticism, and the principles that have guided the company through both its highest milestones and its most difficult periods. A session for founders, executives, and anyone navigating the tension between institutional safety and transformative risk.
Building a new food category required Uma Valeti to maintain conviction while operating in conditions designed to erode it: early scientific uncertainty, a skeptical investment community, no established regulatory pathway, and sustained media criticism. In this keynote, he examines the leadership behaviors that allowed UPSIDE Foods to reach federal approval and unicorn valuation, and what the company has learned as it now confronts the harder problem of commercial scale. Practical, honest, and unusually specific, this session is designed for senior audiences who have moved past inspiration and want the operational reality of transformational leadership.
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