David Sinclair Keynote Speaker and Harvard Longevity Scientist

David Sinclair

World's Foremost Authority on Human Longevity | Professor of Genetics, Harvard Medical School | Co-Founder, Life Biosciences | Bestselling Author of 'Lifespan'

What if aging itself could be treated, slowed, or reversed? Few scientists have done more to make that question credible than David Sinclair. Professor of Genetics at Harvard Medical School and co-founder of Life Biosciences, Sinclair has reframed aging as a treatable condition and brought the science of longevity from the lab to the executive stage. Audiences gain a clear view of the breakthroughs reshaping health, healthcare, and human potential.

Want to book David Sinclair as a speaker for your event? Please provide the info below and we’ll get in touch within 24h:

    David Sinclair biography

    Longevity speaker David Sinclair is widely regarded as one of the world’s foremost authorities on the biology of aging and one of the most influential scientific voices arguing that aging can be slowed, treated, and even reversed. He is Professor of Genetics at Harvard Medical School, co-director of the Paul F. Glenn Center for Biology of Aging Research, and the author of the international bestseller Lifespan: Why We Age and Why We Don’t Have To.

    Longevity speaker David Sinclair has spent more than two decades at the frontier of aging research. His lab has published over 200 scientific papers and produced more than 50 patents, with his work appearing in Nature, Science, and Cell. He is the architect of the Information Theory of Aging, which proposes that aging is driven by a loss of epigenetic information rather than irreversible damage, and that lost information can be restored, opening a path toward biological rejuvenation.

    Sinclair has translated his science into companies that are reshaping the longevity industry. He co-founded Sirtris Pharmaceuticals (acquired by GSK), MetroBiotech, and Life Biosciences, which is now developing partial epigenetic reprogramming gene therapies that have received FDA clearance to enter human clinical trials. His Lifespan podcast brings his research to a global audience, and Time magazine has named him to its 100 Most Influential People in the World and Top 50 People in Healthcare lists.

    From Lab to Clinic: The Information Theory of Aging

    Sinclair’s central scientific contribution is the idea that aging behaves like information loss in a system, similar to scratches on a CD that disrupt the music underneath. His lab has demonstrated in animal models that partial cellular reprogramming can restore vision, repair tissues, and reverse markers of biological age. These findings are now moving into human trials through Life Biosciences and are being tested against the Information Theory of Aging at clinical scale.

    As a speaker, David Sinclair brings senior audiences inside the most important scientific story of our generation: the shift of aging from an inevitability to a treatable condition. He addresses what the next wave of longevity science means for healthcare systems, life sciences investment, insurance, talent strategy, and personal health, translating complex biology into clear, decision-ready insights for executives, investors, and policymakers.

    David Sinclair Speaking Videos

    David Sinclair - Is Aging Reversible? A Scientific Look with David Sinclair
    David Sinclair - Why We Age and Why We Don't Have To

    David Sinclair Keynote Topics

    Sinclair takes audiences inside the breakthroughs from his Harvard lab and the wider longevity field, showing how partial epigenetic reprogramming, sirtuin activation, and NAD+ pathways are being used to restore youthful cell function. He explains, in clear language, why these findings have moved aging research from speculative theory to human clinical trials, and what it would mean for medicine if biological age could be measurably reversed.

    Most of medicine treats diseases one at a time. Sinclair argues that the single most powerful intervention available to us is to treat aging itself, the upstream cause of cancer, Alzheimer's, cardiovascular disease, and most chronic illness. In this keynote, he lays out what this shift means for hospitals, insurers, pharma, and governments, and how leaders should prepare for a world in which extending healthspan, not just lifespan, becomes the central goal of healthcare.

    Sinclair's central scientific thesis is that aging is not damage but the loss of biological information, and that lost information can be recovered. Drawing on his own research and findings from labs worldwide, he walks audiences through the science behind the theory, the experiments that have validated it in animal models, and the human trials now testing whether the same principles apply to people. A talk for audiences that want to understand the actual mechanism behind longevity, not just the promise.

    Longevity is no longer a niche science topic. It is a fast-emerging economic sector that touches biotech, consumer health, finance, insurance, real estate, and workforce planning. Sinclair offers a grounded view of where the longevity industry is going, which therapies and platforms are likely to matter, and how executives can think about long-term strategy when human healthspan itself becomes addressable.

    FAQs on Booking David Sinclair

    Why David Sinclair?

    Booking David Sinclair for your event delivers a rare combination: one of the most cited scientific voices in longevity research, a Harvard professor whose lab has produced more than 200 papers and over 50 patents, and a serial entrepreneur whose biotech ventures are now moving aging therapies into human clinical trials. Sinclair brings credibility, clarity, and conviction to a topic that most leaders sense will reshape their industry but few feel equipped to navigate. Audiences leave understanding not only what is happening in longevity science but what it means for their organization, their healthcare systems, and their own lives. Aurum Speakers Bureau can arrange a keynote, fireside conversation, or strategic briefing with David Sinclair tailored to the questions your senior audience actually has.

    Can David Sinclair really reverse aging?

    Sinclair's lab and others have demonstrated in animal models that aspects of biological aging can be slowed and, in some cases, reversed using approaches such as partial epigenetic reprogramming, sirtuin activation, and pathways involving NAD+. Life Biosciences, which he co-founded, has received FDA clearance to begin human clinical trials of a gene therapy designed to rejuvenate cells in patients with certain eye conditions. Sinclair himself emphasizes that these are early human trials and that scientific claims must be tested rigorously. His broader thesis, that aging is a treatable condition rather than an inevitability, is increasingly mainstream within longevity research.

    What is David Sinclair's book Lifespan about?

    Lifespan: Why We Age and Why We Don't Have To, published in 2019, lays out Sinclair's central argument that aging is a disease and a treatable one. Drawing on decades of research at Harvard and beyond, the book introduces the Information Theory of Aging, explains the role of longevity genes and sirtuins, and describes the lifestyle and biomedical interventions Sinclair believes can extend healthspan. It became an international bestseller, has been translated into more than thirty languages, and is widely credited with bringing longevity science into mainstream conversation.

    What topics does longevity speaker David Sinclair cover in his keynotes?

    David Sinclair speaks on the science of aging and cellular rejuvenation, the Information Theory of Aging, the future of healthcare, the longevity economy, healthspan as the new frontier of medicine, and how individuals and organizations can prepare for a world in which biological age becomes addressable. He is especially valuable for healthcare executives, biotech and life sciences leaders, investors, insurers, and senior audiences thinking about long-term strategy and human capital. To book David Sinclair as a keynote speaker, contact Aurum Speakers Bureau.

    How to book David Sinclair as a keynote speaker?

    Aurum Speakers Bureau can help you book David Sinclair as a speaker for your next event, conference, or board meeting. Simply fill out our contact form to inquire about David Sinclair's availability for a speaking engagement. One of our booking agents will respond to your request immediately and contact the speaker to let them know you want to hire them. We will assist you with obtaining speaking fees, booking information, and confirming availability for David Sinclair or any other top keynote speaker or celebrity of your choice.

    How much is David Sinclair speaking fee?

    David Sinclair speaking fees are determined by several factors, including the event's date, whether it's a virtual or in-person event, the duration, format, preparation required for their speech, and more. The same applies to the cost to hire any other top expert speakers and celebrities. The Speaker Fee Range listed on our website is simply a guideline and is subject to change without notice. If you would like to hire David Sinclair to deliver a keynote speech for your event, please fill out the contact form or email us at info@aurumbureau.com with as much detail as possible. One of our experienced agents will get in touch with you and let you know exactly how much it will cost to book David Sinclair.

    How can I contact David Sinclair?

    We only work with David Sinclair on paid speaking engagements. Aurum Speakers Bureau can assist you in booking David Sinclair and will handle all negotiations, contracts, and logistics associated with having David Sinclair speak at your event. We will be your sole point of contact throughout the process. Get in touch with Aurum Speakers Bureau today, and we will reach out to any motivational speaker or celebrity you want to enquire about speaking at your event. If you wish to contact David Sinclair for any other reason, we will be unable to assist you as we are not authorized to provide personal contact information.

    Can I book David Sinclair for a virtual keynote?

    Yes, David Sinclair is available for virtual keynotes and webinars. To book David Sinclair for a virtual event, please complete the contact form or send us an email to inquire about the special fees for virtual engagements.